The Sewer Lair is the home of the Turtles, located in an abandoned subway station beneath Chinatown, New York City. The lair has been seen many times over several episodes. It is furnished with a kitchen, living room with TV, bedrooms for the turtles and Master Splinter, a dojo for practicing ninjutsu. It also has a workshop for Donnie and a meditation room for Master Splinter. It is wired for electricity to power the lights and many video games the turtles have collected as well as Donnie's power tools. Despite being located in such a place as a sewer, the lair appears comfortable enough that visitors like April and Casey don't seem put off by it.
- Living Room
- The Dojo
- Donnie's Workshop
- It is destroyed in The Invasion by Kraang Subprime and the Kraang.
- It is rebuilt in Casey Jones VS the Underworld.